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All Stem Cells Aren’t Created Equal. Dr. Greenberg Explains what Stem Cell Types Are Used at GRM and How They Aid Healing.

Stem cell therapy is one of the most exciting frontiers in modern medicine, offering treatments for a wide range of conditions from orthopedic injuries to neurological disorders.  There are a variety of different types and sources of stem cells, but not all of them are created equal. 

At Greenberg Regenerative Medicine, we pride ourselves on using the most advanced and effective types of stem cells available: adipose derived stem cells and VSELs. Read on to find out what sets these cells apart.


Understanding Stem Cell Sources

Stem cells are unique because of their ability to transform into various types of cells in the body, making them invaluable for regenerative treatments. These cells can come from a variety of sources, and where they come from determines their efficacy.

Many clinics, particularly those outside the US, utilize stem cells derived from placental tissue. These cells are harvested from the placenta immediately after birth and have been lauded for their potential in treating many conditions.

However, due to their large size, these cells tend to become trapped in the lungs when administered intravenously. As a result, they often fail to reach and repair the target organs or tissues, and their effectiveness is limited.

Bone marrow is another common source of stem cells. Usually used in orthopedic treatments, bone marrow-derived stem cells are harvested directly from the patient’s own bones. The concentration of stem cells in bone marrow is relatively low compared to other sources, and bone marrow extraction is invasive and painful.


The Greenberg Approach: Adipose-Derived Stem Cells and VSELs

At Greenberg Regenerative Medicine, we employ two main types of stem cells: those derived from adipose (fat) tissue and Very Small Embryonic-Like Stem Cells (VSELs).


Adipose-Derived Stem Cells

One of the primary sources of stem cells at Greenberg Regenerative Medicine is adipose tissue, which is harvested from the patient’s own fat cells. Stem cells are plentiful in adipose tissue and this method offers advantages over bone marrow and placental derived cells. 


The concentration of stem cells in fat tissue is significantly higher than in bone marrow, minimizing the invasiveness of the procedure. Adipose tissue contains not only stem cells but also pericytes and preadipocytes. These cells are effective at rebuilding cartilage and enhancing tissue repair. 


Very Small Embryonic-Like Stem Cells (VSELs)

VSELs represent one of the most groundbreaking discoveries in modern regenerative medicine. These cells are exceptionally small, which allows them to navigate through the bloodstream, cross the blood-brain barrier, and reach various tissues and organs much more effectively than larger stem cells.  VSELs are also known for their ability to rapidly multiply and produce a high amount of growth factors and proteins. When combined with their small size, it’s a one, two punch to treat the most challenging conditions.


Why GRM’s Approach is Superior

When considering regenerative medicine, your  choice of stem cell source can determine how successful your treatment will be. Greenberg’s adipose-derived stem cells and VSELs are on the cutting edge of stem cell treatments, and have several advantages over the competition.

  1. Higher Efficacy: Adipose-derived stem cells have a higher concentration of stem cells and additional supportive cells. VSELs, being smaller and able to permeate bodily membranes easier, can reach and repair more tissues and organs than larger stem cells.
  2. Better Delivery and Targeting: The small size of VSELs allows them to bypass difficult membranes such as the blood-brain barrier and pulmonary filtration, enabling more efficient delivery to the target tissues.
  3. Minimally Invasive Procedures: Harvesting adipose tissue for stem cell extraction is less invasive and less painful compared to bone marrow harvesting. This means patients experience less discomfort and a quicker recovery time.
  4. Personalized Treatment: By using stem cells derived from the patient’s own body, Greenberg ensures a more personalized and compatible treatment. This approach minimizes the risk of rejection and maximizes the potential for successful outcomes.

 

At Greenberg Regenerative Medicine, our use of adipose-derived stem cells and VSELs reflects our commitment to staying on the cutting edge of regenerative medicine. By focusing on patient-centered approaches and cutting-edge science, we aim to provide the best possible regenerative medicine treatments to our patients. 

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