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What should I expect during my first visit?

To assess if regenerative stem cell treatments can help you, Dr. Scott Greenberg and his team will review your medical history, pertinent radiographic studies such as X-rays and MRIs, and perform a Comprehensive Kinetic Diagnosis that includes a hands-on examination of the site of your physical complaint and all areas related to it plus evaluation of how the body moves.  Developed by Dr. Greenberg, a Comprehensive Kinetic Diagnosis seeks to identify the root cause of your pain and create a roadmap for joint regeneration that resolves the core problem and eliminates many of your symptoms.

A Comprehensive Kinetic Diagnosis enables the treatment team to rebalance your body, remove stressors on your affected joint, remove pressure from painful structures, and return your body to a healthy equilibrium. After the Comprehensive Kinetic Diagnosis, Dr. Greenberg will discuss what regenerative therapies he recommends for your condition. Together, you will come up with an individualized treatment plan. 

What regenerative therapies do you offer?

We offer stem cell therapy, platelet-rich plasma, prolotherapy, and IV nutrition therapy. Based on your condition, Dr. Greeneberg may recommend one or more of these treatments. 

Stem Cell Therapy uses the mesenchymal stem cells and biological growth factors to heal and regenerate injured tissue such as ligaments, tendons, joints and cartilage. When combined with Platelet Rich Plasma (PRP) treatment, a stem cell treatment is turbocharged with more growth factors and cells that have a greater ability to recruit the immune system to heal.

Platelet Rich Plasma (PRP) are concentrates of platelets and growth factors derived from the patient’s own blood, and then are injected with pinpoint precision into damaged and pain causing areas. The purpose of PRP is to enable the body to naturally heal chronic areas of damage that have not healed on their own.  

In prolotherapy, Dr. Greenberg injects substances such as dextrose and lidocaine at the site of pain. Prolotherapy causes a minor therapeutic reaction that alerts your body to proliferate blood cells and healing components that are sent to the injection site.

IV therapy refers to the intravenous administration of nutraceuticals (vitamins, minerals, and biological compounds) to promote healing, support bodily functions, and promote longevity and wellness. There are several different kinds of IV therapies, each tailored to a specific ailment. Dr. Greenberg works with each patient to determine the best combination of nutrients for them to promote healing, immune support, hydration, and nourishment.

What is the treatment process like?

For stem cell therapy, a local anesthetic is used to numb both the harvest and treatment region when possible. The harvest area is the site where your cells are drawn from your adipose (fat) tissue using two very small incisions. They are then prepared according to FDA guidelines by your Stem Cell Therapy team. Dr. Greenberg will then perform a comprehensive treatment to the damaged region and related areas that further contribute to the source of pain and joint dysfunction. Often, the adipose is used as a fat graft in patients who have joint damage in knees, ankles, hips, shoulders, elbows and thumbs, while patients with neck and back pain will receive direct treatment to areas of the spine and sacrum.

For platelet-rich-plasma, blood is drawn from the patient much like during a blood test. The blood is sent to the lab, where it is filtered. Generally, a sample of whole blood contains about 93% red blood cells, 6% platelets and 1% white blood cells (WBC). To create PRP, the sample that was drawn is placed in a centrifuge where the platelets and white blood cells are separated from the red blood cells. The mixture is inverted in terms of the proportions. 

The concentration of the red blood cells, which do little to promote healing, is reduced to around 5%. Beneficial platelets and white blood cells (WBC) are increased to about 94% in the sample. Your physician will then inject the platelet-rich plasma in and around the damaged joint or tissue to initiate the regeneration process. (The PRP sample may also contain a small amount of harmless anticoagulant similar to vitamin C.)

Are regenerative therapies an effective alternative to surgery?

Regenerative treatments are shown to significantly reduce pain and improve joint function and quality of life. Prolotherapy, Platelet-Rich Plasma, and Stem Cell Treatments are excellent alternatives to pain management or surgery. Surgical patients developed four times as many complications than nonsurgical patients, including infections, blood clots, and knee stiffness that requires another procedure to fix. Dr. Greenberg is especially sought after by individuals who have not been helped by physical therapy, chiropractic treatments, osteopathy, steroid injections or surgery.  

How many treatments will I need? How long will the results last?

Every patient is different, factors also include age, the severity of the injury, immune response, and the rate of healing to consider. For some patients, positive results may be felt within a week. Other patients may require several months of healing. It is essential to keep in mind that the treatment is activating your body to heal itself by regenerating soft tissue. You have to give the cell structures time to grow back.  With correction of pelvic tilt, which is commonly seen, patients may experience less limping and feel a greater sense of balance. This correction can also reduce pressure to the lumbar spine.

What kind of therapy will I need?

Your condition, the severity of your pain or dysfunction, your medical history, and other factors such as age, immune response, and the rate of healing will determine what kind of treatment protocol Dr. Greenberg recommends for you. Oftentimes, you will be recommended a combination approach with more than one type of regenerative therapy. Stem cell therapy and platelet-rich plasma are commonly combined. Prolotherapy can also be combined with them or be used on its own.

How much experience does Dr. Greenberg have?

For the past twenty years, Dr. Greenberg has studied the behavior of stem cells and researched their complex nature. Since 1999, he has researched how tissue-specific stem cells function in the body, how they regenerate nerve, joint and tissue systems and how they depend on other blood components to heal an injury. He will typically perform several hundred stem cell procedures and a few thousand PRP treatments per year.

Dr. Greenberg is a pioneering leader in developing new stem cell-based therapies. He serves as the chair of the Institutional Review Board of the American Association of Stem Cell Physicians and is a founding board member. He is also a consulting physician for DSM, a leader in regenerative biological medicine. He was a member of the first team to publish a case study to repair a meniscus tear using autologous stem cell therapy. He also has the distinction to be selected and accredited as Director of the Regenerative Medicine team at the Dee Adams Center for Integrative and Regenerative Medicine at the Bryn Mawr Hospital.  Dr. Greenberg has lectured nationally and internationally, and currently teaches doctors and residents. 

Dr. Greenberg is a member of the American College for Advancement in Medicine and a member of the American Association of Orthopedic Medicine. He holds Board Certification in Family Practice and is a recipient of the Physicians Recognition Award from the American Medical Association. He is a diplomate of the National Board of Medical Examiners.

What is the average cost? Is it covered by insurance?

The initial consultation is $495. During this visit, Dr. Greenberg will evaluate your condition and recommend a treatment approach. This evaluation is typically an hour.  Furthermore, in most cases a portion of the consultation fee will be applied to the initial treatment. The number of visits you will require will determine the overall price of the treatment process. Greenberg Regenerative Medicine does not accept insurance but will provide a bill for you to submit to your provider. Patient CareCredit financing is available and can be done via a patient portal. We offer a discount to current and retired armed forces members, first responders, and Main Line Health employees.

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