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The Science Behind PrP Gel: A Q&A with Dr. Scott Greenberg

dr scott greenberg

At Greenberg Regenerative Medicine, we honor the traditional treatment methods employed in our practice that have brought relief for countless patients—but we also remain focused on the evolution of medical technology to broaden our spectrum of healing capabilities. One of the newest introductions to the regenerative medicine space is PrP Gel, an evolution of traditional platelet-rich plasma treatments that aims to amplify healing and rejuvenation.

We sat down with Dr. Scott Greenberg to discuss what makes PrP Gel unique, where he sees the greatest potential, and why GRM continues pushing forward even when existing treatments are already successful.


Q: What is PrP Gel, and what makes it different from the standard PrP currently used in your office?


A: “The gel is actually made from something called PPP, or platelet-poor plasma. It’s a way of taking the plasma and putting it through a process of heating and cooling that transforms it into a gel that can be used for injection.

Traditional PrP is more liquid in form. With PrP Gel, we’re able to create a structure that can stay in place differently and potentially provide additional support in the treated area.”

Q: Even in the early stages of adoption, what have you found most promising or compelling about PrP Gel so far?


A: “One of the most exciting aspects is that this gel appears to boost the amount of regenerative healing factors by about four times.

We also think the gel itself may provide cushioning within the joints, which is something a liquid on its own cannot really do. That combination of regenerative potential and structural support is very compelling.”

Q: What can you share about the safety of PRP Gel, especially for patients who may be hesitant about newer regenerative treatments?


A: “PRP gel is considered a low-risk treatment because it is autologous, meaning it’s made from the patient’s own blood. This reduces the risk of allergic reactions or rejection since no outside biological material is being introduced into the body. While all medical procedures carry some level of risk, using the patient’s own natural growth factors offers a strong safety advantage compared to treatments involving donor tissues or unregulated biologic products. In some cases, complications have been reported from procedures performed outside regulated medical settings, including infections linked to injected donor-derived products.’

Q: PrP Gel is an emerging technology in the regenerative medicine world. Why continue exploring new treatment modalities when traditional methods are already successful?


A: “I think we are always exploring ways to provide the best results for our patients. It’s important not to simply rest on past successes, but to constantly think about what can be improved.

For example, we used to use fat harvesting stem cell procedures frequently for patients with neck and back issues. Several years ago, we began developing treatments using VSEL injections in these areas and saw superior results, especially with radiculopathy, or nerve pain and damage. We were able to achieve those results without surgically harvesting fat from the patient, which was a tremendous breakthrough.”

Q: What does being an early adopter of technologies like PrP Gel say about GRM’s philosophy as a practice?


A: “It’s all about trying to provide the best results for our patients in the shortest amount of time possible. Fortunately, my understanding of certain aspects of biomedical engineering allows me to grasp concepts of how we can continue refining our systems and treatments for optimal results.”


At GRM, innovation is approached with both curiosity and caution. New technologies are not adopted simply because they are new, but because they show meaningful potential to improve patient experience, recovery, and long-term outcomes.


Q: How do you evaluate whether a new regenerative treatment is worth introducing into the practice?

A: “It really comes down to understanding the scientific rationale, and then seeing how we can apply that toward the most beneficial patient outcomes.”


Every emerging treatment begins with research, scientific understanding, and real-world applicability at Greenberg Regenerative Medicine. The goal is always to balance innovation with thoughtful clinical decision-making, ensuring that any new therapy introduced aligns with the practice’s patient-first philosophy.

Q: What kinds of aesthetic or regenerative concerns do you believe PrP Gel may be especially well suited for?


A: “In aesthetics, it can be placed through a cannula under the skin to help rejuvenate, tighten, and brighten the skin. For regenerative medicine, I think it can help patients with arthritis in articular joints such as the hip, knee, ankle, or shoulder. It may also help with certain cases of rotator cuff tears, labral tears, and meniscus tears of the knee. For both applications, it can be used with or without VSELs infused into the gel. These specialized stem cells further supercharge the regrowth of the treated area.”


Looking Ahead

Regenerative medicine is evolving rapidly. Treatments like PrP Gel represent a broader shift in medicine toward therapies designed not only to manage symptoms, but to support the body’s own healing mechanisms in smarter, more targeted ways.

At GRM, that pursuit of better outcomes continues to drive the exploration of technologies that may help patients recover faster, feel better, and regain quality of life with less invasive approaches.


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