You may have heard of the term biohacking, but do you know what it really means? Biohacking is the practice of using natural methods to help the body function at its optimal level. In some cases, biohacking can even slow or reverse some aspects of the body’s aging process. While the concept may sound complex, its foundation lies in simple, consistent habits that improve cellular health, energy, and resilience.
Foundations of Biohacking
Effective biohacking begins with the basics. The most simple methods include sleeping sufficiently (7-8 hours nightly), moving daily through exercise and stretching, and eating a whole-food diet rich in nutrients. These habits provide the body with the building blocks needed for peak performance.
Dr. Greenberg shares that, “A nutritious diet is one of the most impactful ways to influence physical and mental wellbeing. Consistent exercise, which can be done anywhere, remains equally vital. Together, these two lifestyle factors form the cornerstone of sustainable health optimization.”
For Dr. Greenberg, biohacking is also about caring for mental wellness. In his free time, Dr. Greenberg focuses on self-enrichment through activities that bring him joy, whether it’s surfing, boxing, biking, or spending time with his family.
Supporting Cellular Health with Supplements
Targeted supplementation can augment nutrition by supporting energy, immune function, and cellular repair. Greenberg Regenerative Medicine offers a curated selection of physician-grade supplements in our office and on our webstore to help fill nutritional gaps, ensuring patients have access to trusted, clinically vetted options that meet the highest standards of purity and efficacy.
In addition to his healthy diet, Dr. Greenberg himself takes a whopping 12 supplements daily! From Resveratrol and Quercetin to Active Nutrients and Heart Gems, he ensures to support his health through a simple, daily commitment to taking his vitamins. One widely recommended product by Dr. Greenberg, Pure Defense, has shown notable success in maintaining immune resilience and reducing the frequency of common illnesses. Regular use of immune-supporting nutrients can help the body sustain high levels of performance and recovery.
Greenberg Regenerative Medicine offers specialized regenerative therapies designed to support overall vitality, helping patients feel more energetic, vibrant, and youthful from the inside out. Modalities such as systemic VSELs (very small embryonic-like stem cells) have been used to promote energy, renewal, and longevity at the cellular level. Dr. Greenberg has personally used VSELs to maintain optimal health and biologically halt the aging process. This procedure has also been recognized by the FDA as promising for treating progeria, a rare genetic disorder causing accelerated aging in children, and it’s currently being prioritized for faster evaluation and potential approval.
Lessons from the Father of Biohacking
Dave Asprey, often referred to as the father of biohacking, played a key role in introducing biohacking to the mainstream. His work emphasizes practical methods that show everyday people how to use data, nutrition, light, sleep, and targeted supplements to improve energy and performance. Asprey has taught the importance of accessibility in biohacking, where simple, doable practices make all the difference. Some of his core principles include:
Start with fundamentals that meaningfully raise cellular energy (sleep, light, minerals, protein) before chasing fancy hacks.
Personalize through data, using laboratory testing to pinpoint your specific needs.
Be consistent, as small, repeatable actions create lasting results.
“Thanks to advancements in science and technology, we are entering a groundbreaking era of precision health. In this era, every individual has the power to manage their unique nutritional needs effectively,” Asprey shares in his blog. “Personalized supplements are the future, transcending mere questionnaires. Our bodies are complex ecosystems, signaling our specific nutrient requirements based on our unique inner environments. With the right tools, we can tailor our supplement routines to these signals.”
Dr. Greenberg had the exciting opportunity to meet Dave Asprey at the A4M Conference in Las Vegas. Dr. Greenberg stood by as Asprey tossed back a fistful of his daily supplements on camera all at once—no drama, just a practice routine. That simple act captured Dr. Greenberg’s biggest takeaway from him: the power of a clear, compelling message that moves people from interest to action. When healthy habits are presented in a straightforward and attainable way, people are far more likely to follow through. In medicine, it’s that consistency that matters most.
The Importance of Quality and Consistency in Biohacking
When it comes to supplementation, fewer products taken consistently often outperform an overwhelming regimen done sporadically. It’s crucial to focus on taking high-quality supplements, and to choose amounts that match your goals and your labs. Key indicators of a high-quality supplement include:
Third‑party testing: Look for USP, NSF/Certified for Sport, or IFOS (for omega‑3) verification.
Bioavailable nutrient forms: e.g., magnesium glycinate/taurate, methylcobalamin + methylfolate for B12/folate, chelated minerals.
Transparent labels: No proprietary blends, doses you can verify.
Clean, minimal excipients and no artificial additives, dyes or titanium dioxide when possible.
The easiest way to incorporate biohacking into any lifestyle is to build new habits that don’t require a big shift in everyday routines. Here are some practical adherence tips shared in our office in the greater Philadelphia area:
Pair supplements with an existing routine (morning coffee, evening skincare, etc.)
Use a weekly pill organizer tray, available at Greenberg Regenerative Medicine offices for patient convenience.
Carry a travel pouch to avoid missed doses when away from home.
Recheck key labs 1-2 times per year to ensure continued alignment with individual needs—supplementation should evolve with your biology.
Track one or two outcomes that matter to you (energy, sleep quality, HRV, training recovery) for 30-60 days.
What Dr. Greenberg Learned from Dave Asprey
Biohacking is not about doing more—it’s about doing what matters most, better. By focusing on foundational health practices, incorporating advanced regenerative therapies, and maintaining consistency, individuals can enhance cellular energy, strengthen immunity, and improve overall longevity.
A final note from Asprey’s blog: “In the quest for optimal health and longevity, understanding how to nourish our cells has never been more crucial.” Biohacking, ultimately, comes from caring for your body on the cellular level to support your health in the bigger picture.
